Join Us: Careers & Culture

At Bicara, we bring together the agility and passion of a startup with the confidence and focus of an established biopharma. Our team is dynamic, diverse and driven — and we have proven that we can deliver, with a first IND and lead program already in the clinic.

Together, we are determined to bring high-impact, first-in-class medicines to cancer patients.

Interested in joining the Bicara team?

The Director of Translational Medicine at Bicara Therapeutics will play a critical role in advancing the company’s mission to develop innovative tumor targeting molecules for the treatment of cancer. They will be responsible for developing, leading, and executing the translational and biomarker strategy of the company. In partnership with our research and clinical teams, this individual will be responsible for investigating various aspects of the biomarker strategy including patient stratification biomarkers, patient response biomarkers, mechanism of action, and mechanism of resistance which may lead to further combination strategies. The ideal candidate will thrive in a collaborative and team-oriented environment and help foster a culture of scientific excellence, innovation, and teamwork. This person will report to the SVP, Research & Development Strategy and Operations with a dotted line to the Chief Medical Officer.


  • Develop and implement global clinical biomarker strategies for our lead clinical oncology program BCA101 and any further pipeline assets.
  • Manage and oversee external collaborations with academic institutions, contract research organizations, and other partners in the field of translational research and biomarkers.
  • Lead the development and validation of biomarker assays for clinical use, including proficiency testing, analytical validation, and clinical validation.
  • Analyze biomarker data and present summaries to support clinical decision-making.
  • Responsible for communicating biomarker data to internal stakeholders, external partners, and regulatory authorities.
  • Participate in the preparation of regulatory submissions related to biomarkers for oncology programs.
  • Represent the company’s scientific expertise and capabilities to external stakeholders which may include scientific publications and presentations.
  • Work closely with the research team on pre-clinical studies to determine biomarkers that could be leveraged in clinical decision making.


  • PhD in cancer biology, immunology or a related field, with a minimum of 5 years working in the biotechnology or pharmaceutical industry.
  • Strong knowledge of biomarker discovery and development in clinical trials, including assay development, validation, and data analysis.
  • Demonstrated experience in leading clinical biomarker development for innovative early clinical development.
  • Experience in designing pre-clinical studies to elucidate signals and identify potential biomarker strategies moving into the clinic.
  • Self-directed with strong organization and communication skills, capable of leading various aspects of development programs in a fast-paced, results-oriented environment.
  • Demonstrated ability to lead and mentor junior scientists.


Bicara Therapeutics is a clinical-stage biotechnology company developing first-in-class biologics engineered to bring together the precision of targeted therapy and the power of tumor modulators. The company’s bifunctional antibodies are designed to deliver an immunomodulatory payload directly to the tumor microenvironment to ramp up immune cell activity, potentially offering long-lasting efficacy. Bicara’s lead asset, BCA101, a first-in-class EGFR / TGF-β-trap bifunctional antibody, is currently enrolling patients in a Phase 1/1b study. Bicara’s experienced team brings deep expertise across immunology, oncology, clinical development, business development and operational strategy. More information is available at

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply. 

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

To apply, please email your resume/CV to In the subject line include your name and the job title.






















Interested in joining the Bicara team but don’t see an exact fit?
Please submit your CV and a quick explanation of your field of interest to