Join Us: Careers & Culture

At Bicara, we bring together the agility and passion of a startup with the confidence and focus of an established biopharma. Our team is dynamic, diverse and driven — and we have proven that we can deliver, with a first IND and lead program already in the clinic.

Together, we are determined to bring high-impact, first-in-class medicines to cancer patients.

Interested in joining the Bicara team? Please explore our open jobs.

Company Overview:

At Bicara, we are united around a shared purpose: to develop first-in-class dual-action biologics combining the precision of targeted therapy and the power of immunotherapy for patients with cancer. Our approach enables us to activate a powerful immune response precisely at the tumor site, minimizing the potential for systemic side effects.

Just as we bring together two modalities in our dual-action therapies, our work also bridges two continents with a team in Cambridge, Mass. and a dedicated research arm, supported by Biocon, in Bangalore, India. Together we are working towards a shared vision to provide first-in-class, high impact therapies to cancer patients. We are proud of the team we have built, which brings deep expertise across immunology, oncology, clinical development, business development and operational strategy – and if you see yourself at a clinical-stage biotechnology company focused on making a significant impact for cancer patients – Bicara is for you!

Job Summary:

Reporting to our President and COO, this role will be a critical piece of our Cambridge based leadership team. A successful candidate will bring a robust professional background, with experience in demand modeling and supply forecasting, as well as leadership skills. We are looking for someone who is comfortable working collaboratively in a matrix environment and who will be able to serve as a seamless bridge between the Biocon process development group in India and our manufacturing needs.

Job Responsibilities:

  • Manage contract manufacturers
  • Manage supply chain responsibilities, including forecasting, inventory management and storage
  • Work collaboratively with process development and CMC team in India
  • Oversee manufacturing operations to achieve the delivery and profitability goals of the organization

Skills and Qualifications:

  • Academic background in a relevant scientific discipline, advanced degree (MS, PhD or equivalent) preferred
  • Background in process development and supply operations
  • Experience with large molecules and/or antibody manufacturing
  • Collaborative mindset and demonstrated ability to build consensus
  • Minimum of 10 years of relevant work experience in manufacturing, experience in startups and the biotechnology industry a plus 

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply. 

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

To apply, please send your CV and cover letter to careers@bicara.com. In the subject line include your name and the job title.

Company Overview:

At Bicara Therapeutics, Inc., a clinical-stage biopharmaceutical company, we are united around a shared purpose: To develop first-in-class bifunctional antibodies combining the precision of targeted therapy and the power of immunotherapy. Our approach enables us to activate a powerful immune response precisely at the tumor site, minimizing the potential for systemic side effects.

Just as we bring together two modalities in our bifunctional therapies, our team also bridges two continents with teams in Cambridge, Mass. and in Bangalore, India. Together we are working towards a shared vision to provide first-in-class, high impact therapies to cancer patients.

 

Job Summary:

The Director of Translational Medicine is a key member of Bicara’s clinical leadership team and will report to the Chief Medical Officer to help shape and execute Bicara’s strategy to build a biomarker strategy in supporting the development of our pipeline. This role will identify and manage CROs and academic institutions to carry out state-of-the art biomarker studies for demonstrating target engagement/PD effects and confirming MOA of Bicara’s clinical assets. He/She will have proven success in leading the design and generation of clinic-ready biomarker assays to support clinical programs as well as help build strong translational data packages supporting INDs.

Key Responsibilities

  • Collaborate closely with clinical team to implement strategies for translational and clinical biomarker assays using patient samples to define PK/PD/efficacy relationships for advanced assets in preclinical and clinical settings
  • Oversee external vendors, internal teams, and collaborators to develop, qualify, transfer, and validate clinical assays, as well as interpret/analyze biomarker data to support development programs across Bicara’s clinical pipeline
  • Actively participate in troubleshooting and improvement in the quality of the experiments, while ensuring documentation practices are compliant with regulatory expectations on data integrity
  • Ensure delivery of project milestones and timely communication of goals and deliverables to senior management and governance committees
  • Author and review technical reports and summary documents for regulatory filings as well as relevant sections of clinical documents, scientific presentations, and publications
  • Work closely with discovery and clinical teams to develop translational hypothesis, design and implement translational studies to generate data supporting INDs as well as help define biomarker strategies for early preclinical programs

 

Required Qualifications

  • D. or MD Required, PhD/MD preferred along with 5+ years of industry experience
  • Strong work experience in translational research, preferably in human immunology/immuno-oncology, using multiple orthogonal techniques and human tissues such as blood and tumor tissue samples
  • Technical/analytical experience of working with flow cytometer, immunohistochemistry, and -omics based approaches, e.g., single-cell RNA seq analysis, Nanostring, 10X Genomics etc
  • Ability to collaborate seamlessly with CROs and academic collaborators in a fast-paced, dynamic team-oriented environment
  • Knowledge of regulatory expectations and industry standards for clinical biomarker assays
  • Outstanding organizational skills with the ability to prioritize and deliver against timelines and budgets for multiple projects simultaneously
  • Strong interpersonal skills to develop important relationships with team members, cross-functional teams, and all stakeholders to drive problem solving and transparent decisions

 

Here at Bicara, we believe in building diverse teams and cultivating a culture where all voices are included. We encourage people from all backgrounds to apply. 

Bicara Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

 

To apply, please email your resume/CV to careers@bicara.com. In the subject line include your name and the job title.

 

Interested in joining the Bicara team but don’t see an exact fit?
Please submit your CV and a quick explanation of your field of interest to careers@bicara.com